Flights from Madrid to San Francisco

Flights

All filters Price Airlines Time Alliances

Cheap one-way flights

If you're planning to travel one-way to San Francisco, find the best flight deals available here.
American Airlines
DEPARTURE
MAD - SFO
Sat. Jan 9, 2027
Price per a person from
$950
American Airlines
DEPARTURE
MAD - SFO
Sun. Jan 10, 2027
Price per a person from
$1,165
DEPARTURE
MAD - SFO
Sun. Jan 10, 2027
Price per a person from
$1,778
Lufthansa
DEPARTURE
MAD - SFO
Sat. Jan 9, 2027
Price per a person from
$1,795
  1. Despegar
  2. Flights
  3. Flights to North America
  4. Flights to United States of America
  5. Flights to San Francisco
  6. Flights from Madrid to San Francisco
$
Subscribe to these exclusive deals
Please, enter a valid email address
You will receive promotional emails from Despegar. For more information, see (the) privacy policies.
Subscribe to these exclusive deals
Recibí de primera mano nuestras ofertas y beneficios exclusivos.
I want to receive them!
Personalized price alerts News and offers Not-to-be-missed events View privacy policy

Tenemos un nuevo teléfono de atención para Posventa. El número que ves, ya está actualizado.

Browse on the site of:
Iata

Despegar is present on United States of America, Argentina, Bolivia, Brazil, Chile, Colombia, Costa Rica, Ecuador, El Salvador, Guatemala, Honduras, Mexico, Nicaragua, Panama, Paraguay, Peru, Puerto Rico, Dominican Republic, Uruguay

1999-2026, Despegar.com, Inc . All rights reserved.
Find out what's new
Receive first-hand our exclusive offers and benefits.
See more