Flights from Orlando to Santiago

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Cheap one-way flights

If you're planning to travel one-way to Santiago, find the best flight deals available here.
Copa Airlines
DEPARTURE
MCO - SCL
Mon. Nov 16, 2026
Price per a person from
$314
LATAM
DEPARTURE
MCO - SCL
Mon. Nov 16, 2026
Price per a person from
$399
American Airlines
DEPARTURE
MCO - SCL
Mon. Nov 16, 2026
Price per a person from
$409
Delta Air Lines
DEPARTURE
MCO - SCL
Mon. Nov 16, 2026
Price per a person from
$417
Delta Air Lines
DEPARTURE
MCO - SCL
Mon. Nov 16, 2026
Price per a person from
$417
Avianca
DEPARTURE
MCO - SCL
Mon. Nov 16, 2026
Price per a person from
$832
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